Lipocalin-2 promotes adipose–macrophage interactions to shape peripheral and central inflammatory responses in experimental autoimmune encephalomyelitis

Lipocalin-2 promotes adipose–macrophage interactions to shape peripheral and central inflammatory responses in experimental autoimmune encephalomyelitis

Objective: Accumulating evidence suggests that dysfunctional adipose tissue (AT) plays a major role in the risk of developing multiple sclerosis (MS), the most common immune-mediated and demyelinating disease of the central nervous system. However, the contribution of adipose tissue to the etiology...

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Main Authors: Francesca Sciarretta, Veronica Ceci, Marta Tiberi, Fabio Zaccaria, Haoyun Li, Zhong-Yan Zhou, Qiyang Sun, Daniels Konja, Alessandro Matteocci, Anup Bhusal, Martina Verri, Diego Fresegna, Sara Balletta, Andrea Ninni, Claudia Di Biagio, Marco Rosina, Kyoungho Suk, Diego Centonze, Yu Wang, Valerio Chiurchiù, Katia Aquilano, Daniele Lettieri-Barbato
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Molecular Metabolism
Subjects:
Adipose tissue
Immune cells
Lipid metabolism
Mitochondria
Macrophages
Adipocyte
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823001175

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http://www.sciencedirect.com/science/article/pii/S2212877823001175

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