<i>In Silico</i> Mining of Natural Products Atlas (NPAtlas) Database for Identifying Effective Bcl-2 Inhibitors: Molecular Docking, Molecular Dynamics, and Pharmacokinetics Characteristics

<i>In Silico</i> Mining of Natural Products Atlas (NPAtlas) Database for Identifying Effective Bcl-2 Inhibitors: Molecular Docking, Molecular Dynamics, and Pharmacokinetics Characteristics

The Bcl-2 protein has a vital function in controlling the programmed cell doom of mitochondria. If programmed cell death signals are obstructed, an imbalance between cell survival and death will occur, which is a significant reason for cancer. Therefore, the Bcl-2 protein was identified as a possibl...

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Bibliographic Details
Main Authors: Nahlah Makki Almansour, Khaled S. Allemailem, Abeer Abas Abd El Aty, Ekram Ismail Fagiree Ismail, Mahmoud A. A. Ibrahim
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
Bcl-2 protein
cancer disease
MD simulations
molecular docking
pharmacokinetics features
Online Access:https://www.mdpi.com/1420-3049/28/2/783

Internet

https://www.mdpi.com/1420-3049/28/2/783

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