Current progress of cerebral organoids for modeling Alzheimer's disease origins and mechanisms

Abstract Alzheimer's disease (AD) is a progressive, neurodegenerative disease that has emerged as a leading risk factor for dementia associated with increasing age. Two‐dimensional (2D) cell culture and animal models, which have been used to analyze AD pathology and search for effective treatme...

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Bibliographic Details
Main Authors: Sai Sreenivasamurthy, Mahek Laul, Nan Zhao, Tiffany Kim, Donghui Zhu
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10378