Pyrido-pyrimido-thiadiazinones: green synthesis, molecular docking studies and biological investigation as obesity inhibitors

Pyrido-pyrimido-thiadiazinones: green synthesis, molecular docking studies and biological investigation as obesity inhibitors

Obesity is a global public health concern brought on by a combination of excessive dietary intake, inactivity and genetic predisposition. Pyridopyrimidines have received considerable interest in the development of obesity and diabetes. Mannich reaction was applied on 2-thioxo-pyridopyrimidinone deri...

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Bibliographic Details
Main Authors: Ferid Yaccoubi, Mohamed El-Naggar, Fathy M. Abdelrazek, Sobhi M. Gomha, Mohamed S. Farghaly, Tariq Z. Abolibda, Lobna A. Ali, Aboubakr H. Abdelmonsef
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Journal of Taibah University for Science
Subjects:
Pyridopyrimidines
Mannich reaction
multicomponent reactions
molecular docking
binding energy
obesity
Online Access:https://www.tandfonline.com/doi/10.1080/16583655.2022.2159210

Internet

https://www.tandfonline.com/doi/10.1080/16583655.2022.2159210

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