Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria.

Mycobacteria possess different type VII secretion (T7S) systems to secrete proteins across their unusual cell envelope. One of these systems, ESX-5, is only present in slow-growing mycobacteria and responsible for the secretion of multiple substrates. However, the role of ESX-5 substrates in growth...

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Bibliographic Details
Main Authors: Louis S Ates, Roy Ummels, Susanna Commandeur, Robert van de Weerd, Marion Sparrius, Eveline Weerdenburg, Marina Alber, Rainer Kalscheuer, Sander R Piersma, Abdallah M Abdallah, Moataz Abd El Ghany, Alyaa M Abdel-Haleem, Arnab Pain, Connie R Jiménez, Wilbert Bitter, Edith N G Houben
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4418733?pdf=render