Differential usage of DNA modifications in neurons, astrocytes, and microglia

Differential usage of DNA modifications in neurons, astrocytes, and microglia

Abstract Background Cellular identity is determined partly by cell type-specific epigenomic profiles that regulate gene expression. In neuroscience, there is a pressing need to isolate and characterize the epigenomes of specific CNS cell types in health and disease. In this study, we developed an in...

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Bibliographic Details
Main Authors: Kyla B. Tooley, Ana J. Chucair-Elliott, Sarah R. Ocañas, Adeline H. Machalinski, Kevin D. Pham, Walker Hoolehan, Adam M. Kulpa, David R. Stanford, Willard M. Freeman
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Epigenetics & Chromatin
Subjects:
Brain
Epigenomics
Methylation
Hydroxymethylation
Regulatory elements
Genome regulation
Online Access:https://doi.org/10.1186/s13072-023-00522-6

Internet

https://doi.org/10.1186/s13072-023-00522-6

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