Bacteria-derived DNA in serum extracellular vesicles are biomarkers for renal cell carcinoma

This is the first study to determine the clinical importance of circulating bacterial DNA in patients with renal cell carcinoma (RCC). We performed 16S rRNA metagenomic analysis of serum extracellular vesicles (EVs) from 88 patients with RCC and 10 healthy donors and identified three abundant bacter...

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Bibliographic Details
Main Authors: Toshihiro Uemura, Atsunari Kawashima, Kentaro Jingushi, Daisuke Motooka, Takuro Saito, Sassi Nesrine, Toshiki Oka, Yohei Okuda, Akinaru Yamamoto, Gaku Yamamichi, Eisuke Tomiyama, Yu Ishizuya, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Kazutake Tsujikawa, Hisashi Wada, Norio Nonomura
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Heliyon
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023070081