Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo

Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo

Background: MicroRNAs (miRNA) and other components contained in extracellular vesicles may reflect the presence of a disease. Lung tissue, sputum, and sera of individuals with idiopathic pulmonary fibrosis (IPF) show alterations in miRNA expression. We designed this study to test whether urine and/o...

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Bibliographic Details
Main Authors: Sharon Elliot, Paola Catanuto, Simone Pereira-simon, Xiaomei Xia, Shahriar Shahzeidi, Evan Roberts, John Ludlow, Suzana Hamdan, Sylvia Daunert, Jennifer Parra, Rivka Stone, Irena Pastar, Marjana Tomic-Canic, Marilyn K Glassberg
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-12-01
Series:eLife
Subjects:
Urine
Fibrosis
exosomes
microRNA
Online Access:https://elifesciences.org/articles/79543

Internet

https://elifesciences.org/articles/79543

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