Differential Association of the Na+/H+ Exchanger Regulatory Factor (NHERF) Family of Adaptor Proteins with the Raft- and the Non-Raft Brush Border Membrane Fractions of NHE3

Differential Association of the Na+/H+ Exchanger Regulatory Factor (NHERF) Family of Adaptor Proteins with the Raft- and the Non-Raft Brush Border Membrane Fractions of NHE3

Background/Aims: Trafficking, brush border membrane (BBM) retention, and signal-specific regulation of the Na+/H+ exchanger NHE3 is regulated by the Na+/H+ Exchanger Regulatory Factor (NHERF) family of PDZ-adaptor proteins, which enable the formation of multiprotein complexes. It is unclear, however...

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Bibliographic Details
Main Authors: Ayesha Sultan, Min Luo, Qin Yu, Brigitte Riederer, Weiliang Xia, Mingmin Chen, Simone Lissner, Johannes E. Gessner, Mark Donowitz, C. Chris Yun, Hugo deJonge, Georg Lamprecht, Ursula Seidler
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
PDZ-domain adaptor proteins
Ezrin
Salt absorption
Membrane rafts
Cholesterol
Intestine
Online Access:http://www.karger.com/Article/FullText/356577

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http://www.karger.com/Article/FullText/356577

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