Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells.

Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells.

Human CD8(+) regulatory T cells, particularly the CD8(+)CD28(-) T suppressor cells, have emerged as an important modulator of alloimmunity. Understanding the conditions under which these cells are induced and/or expanded would greatly facilitate their application in future clinical trials. In the cu...

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Bibliographic Details
Main Authors: Yuming Yu, Jennifer R Zitzner, Josetta Houlihan, Nancy Herrera, Luting Xu, Joshua Miller, James M Mathew, Anat R Tambur, Xunrong Luo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3237561?pdf=render

Internet

http://europepmc.org/articles/PMC3237561?pdf=render

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