Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription

Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription

Abstract The second messenger cyclic AMP regulates many nuclear processes including transcription, pre-mRNA splicing and mitosis. While most functions are attributed to protein kinase A, accumulating evidence suggests that not all nuclear cyclic AMP-dependent effects are mediated by this kinase, imp...

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Bibliographic Details
Main Authors: Liliana Felicia Iannucci, Anna Maria D’Erchia, Ernesto Picardi, Daniela Bettio, Filippo Conca, Nicoletta Concetta Surdo, Giulietta Di Benedetto, Deborah Musso, Cristina Arrigoni, Marco Lolicato, Mauro Vismara, Francesca Grisan, Leonardo Salviati, Luciano Milanesi, Graziano Pesole, Konstantinos Lefkimmiatis
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41088-x

Internet

https://doi.org/10.1038/s41467-023-41088-x

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