Tissue inhibitors of metalloproteinases (TIMPs) modulate platelet ADAM10 activity

Tissue inhibitors of metalloproteinases (TIMPs) modulate platelet ADAM10 activity

AbstractPlatelet-specific collagen receptor glycoprotein (GP)VI is stable on the surface of circulating platelets but undergoes ectodomain cleavage on activated platelets. Activation-dependent GPVI metalloproteolysis is primarily mediated by A Disintegrin And Metalloproteinase (ADAM) 10. Regulation...

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Bibliographic Details
Main Authors: Christine Shu Mei Lee, Amandeep Kaur, Samantha J. Montague, Sarah M. Hicks, Robert K. Andrews, Elizabeth E. Gardiner
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Platelets
Subjects:
Adhesion
metalloproteinases
platelets
receptors
Timps
Online Access:https://www.tandfonline.com/doi/10.1080/09537104.2023.2288213

Internet

https://www.tandfonline.com/doi/10.1080/09537104.2023.2288213

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