Membrane-induced tau amyloid fibrils

Abstract The intrinsically disordered protein tau aggregates into β-sheet amyloid fibrils that spread in human brains afflicted with Alzheimer’s disease and other neurodegenerative diseases. Tau interaction with lipid membranes might play a role in the formation and spreading of these pathological a...

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Bibliographic Details
Main Authors: Nadia El Mammeri, Olivia Gampp, Pu Duan, Mei Hong
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04847-6