Interleukin-6 modulates colonic transepithelial ion transport in the stress-sensitive Wistar Kyoto rat.
Immunological challenge stimulates secretion of the pro-inflammatory cytokine interleukin (IL)-6, resulting in variety of biological responses. In the gastrointestinal (GI) tract, IL-6 modulates the excitability of sub-mucosal neurons and stimulates secretion into the colonic lumen. When considered...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-11-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00190/full |