Construction of boron-stereogenic compounds via enantioselective Cu-catalyzed desymmetric B–H bond insertion reaction

Enantioselective catalytic methods for the construction of boron-stereogenic compounds are elusive. In this article, the authors describe a route to these compounds via a copper-catalysed desymmetric B-H insertion on 2-arylpyridine-boranes with carbenes.

Bibliographic Details
Main Authors: Guan Zhang, Zhihan Zhang, Mengyuan Hou, Xinping Cai, Kai Yang, Peiyuan Yu, Qiuling Song
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30287-7