Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma
Objective: The current obesity pandemic represents a major health burden, given that it predisposes to the development of numerous obesity-associated disorders. The obesity-derived adipokines not only impair systemic insulin action but also increase the incidence of hepatocellular carcinoma (HCC), a...
Main Authors: | Melanie J. Mittenbühler, Hans-Georg Sprenger, Sabine Gruber, Claudia M. Wunderlich, Lara Kern, Jens C. Brüning, F. Thomas Wunderlich |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-11-01
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Series: | Molecular Metabolism |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877818306781 |
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