Vasoprotective Endothelial Effects of Chronic Cannabidiol Treatment and Its Influence on the Endocannabinoid System in Rats with Primary and Secondary Hypertension

Vasoprotective Endothelial Effects of Chronic Cannabidiol Treatment and Its Influence on the Endocannabinoid System in Rats with Primary and Secondary Hypertension

Our study aimed to examine the endothelium (vascular)-protecting effects of chronic cannabidiol (CBD) administration (10 mg/kg once daily for 2 weeks) in aortas and small mesenteric (G3) arteries isolated from deoxycorticosterone-induced hypertensive (DOCA-salt) rats and spontaneously hypertensive r...

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Bibliographic Details
Main Authors: Marta Baranowska-Kuczko, Hanna Kozłowska, Monika Kloza, Magdalena Kusaczuk, Ewa Harasim-Symbor, Michał Biernacki, Irena Kasacka, Barbara Malinowska
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceuticals
Subjects:
cannabidiol
vascular (endothelial) dysfunction
SHR
DOCA-salt
endocannabinoids
eNOS
Online Access:https://www.mdpi.com/1424-8247/14/11/1120

Internet

https://www.mdpi.com/1424-8247/14/11/1120

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