Phase separation in DNA double-strand break response

ABSTRACTDNA double-strand break (DSB) is the most dangerous type of DNA damage, which may lead to cell death or oncogenic mutations. Homologous recombination (HR) and nonhomologous end-joining (NHEJ) are two typical DSB repair mechanisms. Recently, many studies have revealed that liquid–liquid phase...

Full description

Bibliographic Details
Main Authors: Huan-Lei Liu, Hao Nan, Wan-Wen Zhao, Xiang-Bo Wan, Xin-Juan Fan
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Nucleus
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19491034.2023.2296243