MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's disease
Abstract Introduction Mononuclear phagocytes play a critical role during Alzheimer's disease (AD) pathogenesis due to their contribution to innate immune responses and amyloid beta (Aβ) clearance mechanisms. Methods Blood‐derived monocytes (BDMs) and monocyte‐derived macrophages (MDMs) were iso...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2016-01-01
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Series: | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring |
Subjects: | |
Online Access: | https://doi.org/10.1016/j.dadm.2015.11.004 |