Exploring unconventional targets in myofibroblast transdifferentiation outside classical TGF-β signaling in renal fibrosis
We propose that the key initiators of renal fibrosis are myofibroblasts which originate from four predominant sources—fibroblasts, pericytes, endothelial cells and macrophages. Increased accumulation of renal interstitial myofibroblasts correlates with an increase in collagen, fibrillar proteins, an...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-05-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2024.1296504/full |