A novel splice variant of the human MSTN gene encodes a myostatin‐specific myostatin inhibitor

Abstract Background Myostatin, encoded by the MSTN gene comprising 3 exons, is a potent negative regulator of skeletal muscle growth. Although a variety of myostatin inhibitors have been invented for increasing muscle mass in muscle wasting diseases, no effective inhibitor is currently available for...

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Bibliographic Details
Main Authors: Kazuhiro Maeta, Manal Farea, Hisahide Nishio, Masafumi Matsuo
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Online Access:https://doi.org/10.1002/jcsm.13314