Considerations for skin carcinogenesis experiments using inducible transgenic mouse models

Considerations for skin carcinogenesis experiments using inducible transgenic mouse models

Abstract Objective This study was designed to estimate the percentage of non-malignant skin tumours (papillomas) progressing to malignant squamous cell carcinomas (SCCs) in a carcinogenesis study using established transgenic mouse models. In our skin cancer model, we conditionally induced oncogenic...

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Bibliographic Details
Main Authors: Martyna C. Popis, Rebecca E. Wagner, Fernando Constantino-Casas, Sandra Blanco, Michaela Frye
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Research Notes
Subjects:
Skin carcinogenesis
Mouse model
Papilloma
SCC
p53
k-ras
Online Access:http://link.springer.com/article/10.1186/s13104-018-3182-3

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http://link.springer.com/article/10.1186/s13104-018-3182-3

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