Identification of potential SARS-CoV-2 entry inhibitors by targeting the interface region between the spike RBD and human ACE2

Identification of potential SARS-CoV-2 entry inhibitors by targeting the interface region between the spike RBD and human ACE2

Coronavirus disease 2019 (COVID-19) is a fatal infectious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The virus infection is initiated upon recognition and binding of the spike (S) protein receptor-binding domain (RBD) to the host cell surface receptor, angiotensi...

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Bibliographic Details
Main Authors: Arun Bahadur Gurung, Mohammad Ajmal Ali, Joongku Lee, Mohammad Abul Farah, Khalid Mashay Al-Anazi
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Journal of Infection and Public Health
Subjects:
Receptor-binding domain
RBD
Angiotensin-converting enzyme 2
ACE2
Spike protein
Protein–protein interface
Online Access:http://www.sciencedirect.com/science/article/pii/S187603412030770X

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http://www.sciencedirect.com/science/article/pii/S187603412030770X

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