The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB

The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB

Summary: The nuclear factor κB (NF-κB) pathway plays essential roles in innate and adaptive immunity, but little is known how NF-κB signaling is compartmentalized and spatiotemporally activated in the cytoplasm. Here, we show that the lipogenesis signal cascade Scap-SREBP1-S1P/S2P orchestrates the h...

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Bibliographic Details
Main Authors: Xia Fei, Jiaqi Huang, Fei Li, Yuejue Wang, Zhehua Shao, Lingling Dong, Yinfang Wu, Boran Li, Xue Zhang, Baihui Lv, Yun Zhao, Qingyu Weng, Kaijun Chen, Min Zhang, Shiyi Yang, Chao Zhang, Wen Li, Songmin Ying, Qiming Sun, Zhihua Chen, Huahao Shen
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723005971

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http://www.sciencedirect.com/science/article/pii/S2211124723005971

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