DNA Damage Repair: Predictor of Platinum Efficacy in Ovarian Cancer?

DNA Damage Repair: Predictor of Platinum Efficacy in Ovarian Cancer?

Ovarian cancer (OC) is the seventh most common type of cancer in women worldwide. Treatment for OC usually involves a combination of surgery and chemotherapy with carboplatin and paclitaxel. Platinum-based agents exert their cytotoxic action through development of DNA damage, including the formation...

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Bibliographic Details
Main Authors: Dimitra T. Stefanou, Vassilis L. Souliotis, Roubini Zakopoulou, Michalis Liontos, Aristotelis Bamias
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
ovarian cancer
DNA repair
platinum drugs
effective biomarkers
therapeutic targets
Online Access:https://www.mdpi.com/2227-9059/10/1/82

Internet

https://www.mdpi.com/2227-9059/10/1/82

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