DYRK-family kinases regulate Candida albicans morphogenesis and virulence through the Ras1/PKA pathway

DYRK-family kinases regulate Candida albicans morphogenesis and virulence through the Ras1/PKA pathway

ABSTRACTCandida albicans is an opportunistic human fungal pathogen that causes common superficial mycoses in healthy populations and invasive disease in immunocompromised individuals. The fungus employs several virulence traits to cause disease in humans, including its ability to transition from yea...

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Bibliographic Details
Main Authors: Jessie MacAlpine, Zhongle Liu, Saif Hossain, Luke Whitesell, Nicole Robbins, Leah E. Cowen
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mBio
Subjects:
Candida albicans
Yak1 kinase
DYRK
Ras1/PKA
morphogenesis
dermatitis
Online Access:https://journals.asm.org/doi/10.1128/mbio.02183-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02183-23

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