Nickel(II)-Catalyzed Formal [3+2] Cycloadditions between Indoles and Donor–Acceptor Cyclopropanes

Nickel(II)-Catalyzed Formal [3+2] Cycloadditions between Indoles and Donor–Acceptor Cyclopropanes

This article describes the development of a nickel-catalyzed regio- and diastereoselective formal [3+2] cycloaddition between <i>N</i>-substituted indoles and donor–acceptor cyclopropanes to synthesize cyclopenta[<i>b</i>]indoles. Optimized reaction conditions provide the des...

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Bibliographic Details
Main Authors: Víctor Quezada, Mariña Castroagudín, Felipe Verdugo, Sergio Ortiz, Guillermo Zaragoza, Fabiane M. Nachtigall, Francisco A. A. Reis, Alejandro Castro-Alvarez, Leonardo S. Santos, Ronald Nelson
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Molecules
Subjects:
nickel catalyzed
[3+2] cycloaddition
donor–acceptor cyclopropanes
indoles
cyclopenta[<i>b</i>]indoles
Online Access:https://www.mdpi.com/1420-3049/29/7/1604

Internet

https://www.mdpi.com/1420-3049/29/7/1604

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