Causal relationship between PCSK9 inhibitor and common neurodegenerative diseases: A drug target Mendelian randomization study

Abstract Background In addition to lowering cholesterol levels, the proprotein convertase subtilis kexin 9 (PCSK9) inhibitor has a variety of effects, including anti‐neuroapoptosis. However, the effects of PCSK9 inhibitors on neurodegenerative diseases are controversial. Therefore, we used drug‐targ...

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Bibliographic Details
Main Authors: Qiang Huang, Qin Zhang, Bei Cao
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Brain and Behavior
Subjects:
Online Access:https://doi.org/10.1002/brb3.3543