NLRP12 attenuates ozone-induced pulmonary inflammation by regulating canonical NF-κB Pathway

NLRP12 attenuates ozone-induced pulmonary inflammation by regulating canonical NF-κB Pathway

Ozone (O3) is an important urban air pollutant having strong correlations with respiratory diseases. Several lines of evidence suggest that O3 exposure causes airway hyperresponsiveness (AHR) and pulmonary inflammation. Inhibitory innate immune receptors, such as NLRP12, have been demonstrated to al...

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Bibliographic Details
Main Authors: Mengyuan Li, Yuan Xue, Xinyi Miao, Pengwei Ma, Xiangbing Kong, Yuefei Jin, Yan Li, Wei Wang, Qiao Zhang, Qihong Deng, Feifei Feng
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Ozone
NLRP12
Airway hyper-responsiveness
Lung inflammation
NF-κB
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323007790

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http://www.sciencedirect.com/science/article/pii/S0147651323007790

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