KnotAli: informed energy minimization through the use of evolutionary information
Abstract Background Improving the prediction of structures, especially those containing pseudoknots (structures with crossing base pairs) is an ongoing challenge. Homology-based methods utilize structural similarities within a family to predict the structure. However, their prediction is limited to...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-05-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-022-04673-3 |