RPA and Pif1 cooperate to remove G-rich structures at both leading and lagging strand

In Saccharomyces cerevisiae, the absence of Pif1 helicase induces the instability of G4-containing CEB1 minisatellite during leading strand but not lagging strand replication. We report that RPA and Pif1 cooperate to maintain CEB1 stability when the G4 forming strand is either on the leading or lagg...

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Bibliographic Details
Main Authors: Laetitia Maestroni, Julien Audry, Pierre Luciano, Stéphane Coulon, Vincent Géli, Yves Corda
Format: Article
Language:English
Published: Shared Science Publishers OG 2020-01-01
Series:Cell Stress
Subjects:
Online Access:http://www.cell-stress.com/researcharticles/2020a-maestroni-cell-stress/