ISL1 promotes pancreatic islet cell proliferation.

BACKGROUND: Islet 1 (ISL1), a LIM-homeodomain transcription factor is essential for promoting pancreatic islets proliferation and maintaining endocrine cells survival in embryonic and postnatal pancreatic islets. However, how ISL1 exerts the role in adult islets is, to date, not clear. METHODOLOGY/P...

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Bibliographic Details
Main Authors: Ting Guo, Weiping Wang, Hui Zhang, Yinan Liu, Ping Chen, Kangtao Ma, Chunyan Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3150357?pdf=render