Cytokine Adjuvants IL-7 and IL-15 Improve Humoral Responses of a SHIV LentiDNA Vaccine in Animal Models

Cytokine Adjuvants IL-7 and IL-15 Improve Humoral Responses of a SHIV LentiDNA Vaccine in Animal Models

HIV-1 remains a major public health issue worldwide in spite of efficacious antiviral therapies, but with no cure or preventive vaccine. The latter has been very challenging, as virus infection is associated with numerous escape mechanisms from host specific immunity and the correlates of protection...

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Bibliographic Details
Main Authors: Laury-Anne Leroy, Alice Mac Donald, Aditi Kandlur, Deepanwita Bose, Peng Xiao, Jean Gagnon, François Villinger, Yahia Chebloune
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Vaccines
Subjects:
HIV-1
DNA vaccine
CAEV LTR
LentiDNA
SHIV
IL-7
Online Access:https://www.mdpi.com/2076-393X/10/3/461

Internet

https://www.mdpi.com/2076-393X/10/3/461

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