Requirement of NOX2 expression in both retina and bone marrow for diabetes-induced retinal vascular injury.

Requirement of NOX2 expression in both retina and bone marrow for diabetes-induced retinal vascular injury.

Diabetic retinopathy, a major cause of blindness, is characterized by increased expression of vascular endothelial growth factor (VEGF), leukocyte attachment to the vessel walls and increased vascular permeability. Previous work has shown that reactive oxygen species (ROS) produced by the superoxide...

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Bibliographic Details
Main Authors: Modesto Rojas, Wenbo Zhang, Zhimin Xu, Tahira Lemtalsi, Phillip Chandler, Haroldo A Toque, Robert W Caldwell, Ruth B Caldwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3866146?pdf=render

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http://europepmc.org/articles/PMC3866146?pdf=render

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