Requirement of NOX2 expression in both retina and bone marrow for diabetes-induced retinal vascular injury.
Diabetic retinopathy, a major cause of blindness, is characterized by increased expression of vascular endothelial growth factor (VEGF), leukocyte attachment to the vessel walls and increased vascular permeability. Previous work has shown that reactive oxygen species (ROS) produced by the superoxide...
Main Authors: | Modesto Rojas, Wenbo Zhang, Zhimin Xu, Tahira Lemtalsi, Phillip Chandler, Haroldo A Toque, Robert W Caldwell, Ruth B Caldwell |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3866146?pdf=render |
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