Comprehensive Analysis of CD4+ T Cell Response Cross-Reactive to SARS-CoV-2 Antigens at the Single Allele Level of HLA Class II

Comprehensive Analysis of CD4+ T Cell Response Cross-Reactive to SARS-CoV-2 Antigens at the Single Allele Level of HLA Class II

Common human coronaviruses have been circulating undiagnosed worldwide. These common human coronaviruses share partial sequence homology with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); therefore, T cells specific to human coronaviruses are also cross-reactive with SARS-CoV-2 antig...

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Bibliographic Details
Main Authors: You-Seok Hyun, Yong-Hun Lee, Hyeong-A Jo, In-Cheol Baek, Sun-Mi Kim, Hyun-Jung Sohn, Tai-Gyu Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
CD4+ T cells
cross-reactive T cells
SARS-CoV-2
MHC class II alleles
HLA-DR
HLA-DQ
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.774491/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.774491/full

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