Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient‐derived orthotopic xenografts, cell lines and tumor entities

Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient‐derived orthotopic xenografts, cell lines and tumor entities

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft‐tissue sarcomas with a poor survival rate, presenting either sporadically or in the context of neurofibromatosis type 1 (NF1). The histological diagnosis of MPNSTs can be challenging, with different tumors exhibiting great histolo...

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Bibliographic Details
Main Authors: Edgar Creus‐Bachiller, Juana Fernández‐Rodríguez, Miriam Magallón‐Lorenz, Sara Ortega‐Bertran, Susana Navas‐Rutete, Cleofe Romagosa, Tulio M. Silva, Maria Pané, Anna Estival, Diana Perez Sidelnikova, Mireia Morell, Helena Mazuelas, Meritxell Carrió, Tereza Lausová, David Reuss, Bernat Gel, Alberto Villanueva, Eduard Serra, Conxi Lázaro
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Molecular Oncology
Subjects:
cellular models
MPNST
NF1
PDOX
treatment response
tumor entities
Online Access:https://doi.org/10.1002/1878-0261.13534

Internet

https://doi.org/10.1002/1878-0261.13534

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