Molecular dissection of box jellyfish venom cytotoxicity highlights an effective venom antidote

Box jellyfish venom causes tissue damage, pain, and death through unknown molecular mechanisms. Here, Lau et al. perform a CRISPR screen to identify genes required for venom action and use this information to develop an antidote that blocks venom-induced pain and tissue damage in vivo.

Bibliographic Details
Main Authors: Man-Tat Lau, John Manion, Jamie B. Littleboy, Lisa Oyston, Thang M. Khuong, Qiao-Ping Wang, David T. Nguyen, Daniel Hesselson, Jamie E. Seymour, G. Gregory Neely
Format: Article
Language:English
Published: Nature Portfolio 2019-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09681-1