Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure

Abstract We recently highlighted a novel potential protective paracrine role of cardiac myeloid CD11b/c cells improving resistance of adult hypertrophied cardiomyocytes to oxidative stress and potentially delaying evolution towards heart failure (HF) in response to early β-adrenergic stimulation. He...

Full description

Bibliographic Details
Main Authors: M. Flamant, N. Mougenot, E. Balse, L. Le Fèvre, F. Atassi, E. L. Gautier, W. Le Goff, M. Keck, S. Nadaud, C. Combadière, A. Boissonnas, C. Pavoine
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97493-z