Clinically relevant gene signatures provide independent prognostic information in older breast cancer patients

Abstract Background The clinical utility of gene signatures in older breast cancer patients remains unclear. We aimed to determine signature prognostic capacity in this patient subgroup. Methods Research versions of the genomic grade index (GGI), 70-gene, recurrence score (RS), cell cycle score (CCS...

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Bibliographic Details
Main Authors: Miguel Castresana-Aguirre, Annelie Johansson, Alexios Matikas, Theodoros Foukakis, Linda S. Lindström, Nicholas P. Tobin
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Breast Cancer Research
Online Access:https://doi.org/10.1186/s13058-024-01797-7