Improved Pharmacokinetics and Tissue Uptake of Complexed Daidzein in Rats

Improved Pharmacokinetics and Tissue Uptake of Complexed Daidzein in Rats

The pharmacokinetic profile and tissue uptake of daidzein (DAI) was determined in rat serum and tissues (lungs, eyes, brain, heart, spleen, fat, liver, kidney, and testes) after intravenous and intraperitoneal administration of DAI in suspension or complexed with ethylenediamine-modified γ-...

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Main Authors: Anna Kwiecień, Jana Ruda-Kucerova, Kamil Kamiński, Zuzana Babinska, Iwona Popiołek, Krzysztof Szczubiałka, Maria Nowakowska, Maria Walczak
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
daidzein
γ-cyclodextrin
bioavailability
nonlinear pharmacokinetics
tissue uptake
Online Access:https://www.mdpi.com/1999-4923/12/2/162

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https://www.mdpi.com/1999-4923/12/2/162

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