Deintensification of Adjuvant Treatment After Transoral Surgery in Patients With Human Papillomavirus-Positive Oropharyngeal Cancer: The Conception of the PATHOS Study and Its Development

Deintensification of Adjuvant Treatment After Transoral Surgery in Patients With Human Papillomavirus-Positive Oropharyngeal Cancer: The Conception of the PATHOS Study and Its Development

PATHOS is a phase II/III randomized controlled trial (RCT) of risk-stratified, reduced intensity adjuvant treatment in patients undergoing transoral surgery (TOS) for human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC). The study opened in the UK in October 2015 and, af...

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Bibliographic Details
Main Authors: Sarah Hargreaves, Matthew Beasley, Chris Hurt, Terry M. Jones, Mererid Evans
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Oncology
Subjects:
HPV-related head and neck squamous cell carcinoma
PATHOS
deintensification
transoral surgery
adjuvant
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00936/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00936/full

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