SRBreak: A read-depth and split-read framework to identify breakpoints of different events inside simple copy-number variable regions
Copy-number variation (CNV) has been associated with increased risk of complex diseases. High throughput sequencing (HTS) technologies facilitate the detection of copy-number variable regions (CNVRs) and their breakpoints. This helps in understanding genome structures of genomes as well as their evo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-09-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00160/full |