Metformin attenuates streptozotocin-induced diabetic nephropathy in rats through activation of AMPK signaling pathway

Background: Nephropathy is the main problem of diabetes and can be classified into several phases according to the presence of albuminuria. Adenosine monophosphate-activated protein kinase (AMPK) operates as a sensor of energy charge. Objectives: The aim of our study was to evaluate the reno-protect...

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Main Authors: Amin Hasanvand, Hossein Amini-Khoei, Samane Jahanabadi, Mohammad-Reza Hadian, Alireza Abdollahi, Seyed Mohammad Tavangar, Shahram jtemaei Mehr, Ahmad Reza Dehpour
Format: Article
Language:English
Published: Society of Diabetic Nephropathy Prevention 2018-01-01
Series:Journal of Nephropathology
Subjects:
Online Access:https://nephropathol.com/PDF/jnp-7-37.pdf