PLC regulates spontaneous glutamate release triggered by extracellular calcium and readily releasable pool size in neocortical neurons

PLC regulates spontaneous glutamate release triggered by extracellular calcium and readily releasable pool size in neocortical neurons

IntroductionDynamic physiological changes in brain extracellular calcium ([Ca2+]o) occur when high levels of neuronal activity lead to substantial Ca2+ entry via ion channels reducing local [Ca2+]o. Perturbations of the extracellular microenvironment that increase [Ca2+]o are commonly used to study...

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Bibliographic Details
Main Authors: Maya G. Feldthouse, Nicholas P. Vyleta, Stephen M. Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
spontaneous release
PLC
minis
extracellular calcium
readily releasable pool
calcium-sensing receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1193485/full

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https://www.frontiersin.org/articles/10.3389/fncel.2023.1193485/full

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