Fabrication and Assessment of Orodispersible Tablets Loaded with Cubosomes for the Improved Anticancer Activity of Simvastatin against the MDA-MB-231 Breast Cancer Cell Line

Fabrication and Assessment of Orodispersible Tablets Loaded with Cubosomes for the Improved Anticancer Activity of Simvastatin against the MDA-MB-231 Breast Cancer Cell Line

Various factors limit the use of simvastatin as an anticancer drug. Therefore, this study aimed to analyse simvastatin (SIM)-loaded cubosome efficacy against breast cancer. SIM-loaded cubosomes were prepared using the emulsification method using different glyceryl monooleate, Pluronic F127 (PF-127),...

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Bibliographic Details
Main Authors: Randa Mohammed Zaki, Amal El Sayeh Abou El Ela, Alanood S. Almurshedi, Basmah Nasser Aldosari, Abdullah A. Aldossari, Mohamed A. Ibrahim
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Polymers
Subjects:
cubosomes
simvastatin
breast cancer
Online Access:https://www.mdpi.com/2073-4360/15/7/1774

Internet

https://www.mdpi.com/2073-4360/15/7/1774

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