FAM76B regulates NF-κB-mediated inflammatory pathway by influencing the translocation of hnRNPA2B1

FAM76B regulates NF-κB-mediated inflammatory pathway by influencing the translocation of hnRNPA2B1

FAM76B has been reported to be a nuclear speckle-localized protein with unknown function. In this study, FAM76B was first demonstrated to inhibit the NF-κB-mediated inflammatory pathway by affecting the translocation of hnRNPA2B1 in vitro. We further showed that FAM76B suppressed inflammation in viv...

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Bibliographic Details
Main Authors: Dongyang Wang, Xiaojing Zheng, Lihong Chai, Junli Zhao, Jiuling Zhu, Yanqing Li, Peiyan Yang, Qinwen Mao, Haibin Xia
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-08-01
Series:eLife
Subjects:
FAM76B
hnRNPA2B1
NF-κB pathway
inflammation
neuroinflammation
Online Access:https://elifesciences.org/articles/85659

Internet

https://elifesciences.org/articles/85659

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