15-Deoxy-Δ¹²,¹⁴ prostaglandin J₂ reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice.

15-Deoxy-Δ¹²,¹⁴ prostaglandin J₂ reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice.

AIM: 15-deoxy-Δ¹²,¹⁴ prostaglandin J₂ (15d-PGJ₂) is a ligand of peroxisome proliferator-activated receptor γ (PPARγ) having diverse effects such as the differentiation of adipocytes and atherosclerotic lesion formation. 15d-PGJ₂ can also regulate the expression of inflammatory mediators on immune ce...

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Bibliographic Details
Main Authors: Takahiro Seno, Masahide Hamaguchi, Eishi Ashihara, Masataka Kohno, Hidetaka Ishino, Aihiro Yamamoto, Masatoshi Kadoya, Kaoru Nakamura, Ken Murakami, Satoaki Matoba, Taira Maekawa, Yutaka Kawahito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3189199?pdf=render

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http://europepmc.org/articles/PMC3189199?pdf=render

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