Structural validation and assessment of AlphaFold2 predictions for centrosomal and centriolar proteins and their complexes

Using experimental data, the authors assess the quality and discuss the limitations of AlphaFold2 predictions of protein structures and protein-protein interactions essential for centrosome and centriole biogenesis.

Bibliographic Details
Main Authors: Mark van Breugel, Ivan Rosa e Silva, Antonina Andreeva
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03269-0