Assessing Genomic Mutations in SARS-CoV-2: Potential Resistance to Antiviral Drugs in Viral Populations from Untreated COVID-19 Patients

Assessing Genomic Mutations in SARS-CoV-2: Potential Resistance to Antiviral Drugs in Viral Populations from Untreated COVID-19 Patients

Naturally occurring SARS-CoV-2 variants mutated in genomic regions targeted by antiviral drugs have not been extensively studied. This study investigated the potential of the RNA-dependent RNA polymerase (RdRp) complex subunits and non-structural protein (Nsp)5 of severe acute respiratory syndrome c...

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Bibliographic Details
Main Authors: Daniele Lombardo, Cristina Musolino, Valeria Chines, Giuseppe Caminiti, Claudia Palermo, Irene Cacciola, Giuseppina Raffa, Teresa Pollicino
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Microorganisms
Subjects:
SARS-CoV-2
COVID-19
coronaviruses
antiviral drugs
antiviral therapy
antiviral drug resistance
Online Access:https://www.mdpi.com/2076-2607/12/1/2

Internet

https://www.mdpi.com/2076-2607/12/1/2

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